abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) affects approximately 3 million people in the UK. An 8-week pulmonary rehabilitation (PR) course is recommended under current guidelines. However, studies show that initial benefits diminish over time. OBJECTIVE:We present here an economic evaluation conducted al...

journal_title：Applied health economics and health policy

authors： Burns DK,Wilson EC,Browne P,Olive S,Clark A,Galey P,Dix E,Woodhouse H,Robinson S,Wilson A

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Updated treatment guidelines for atrial fibrillation (AF) have been released by the National Institute for Health and Care Excellence (NICE) in the UK, and highlight a current shortfall in the prescription of anticoagulants to patients with AF for stroke prevention. OBJECTIVE:To design a budget impact model...

journal_title：Applied health economics and health policy

authors： Shields GE,Bates AE,Chapman AM

更新日期：2015-10-01 00:00:00

abstract：CONTEXT:The in-hospital costs of extracorporeal membrane oxygenation (ECMO) have not been well established. OBJECTIVE:To evaluate the in-hospital costs of ECMO technology in both US and non-US settings for all patient types. DATA SOURCES:Systematic review of English-language articles, using the PubMed, Embase, Web of...

journal_title：Applied health economics and health policy

authors： Harvey MJ,Gaies MG,Prosser LA

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:As tuberculosis screening trends to targeting high-risk populations, knowing the cost effectiveness of such screening is vital to decision makers. OBJECTIVES:The purpose of this review was to compile cost-utility analyses evaluating latent tuberculosis infection (LTBI) screening in high-risk populations tha...

journal_title：Applied health economics and health policy

authors： Campbell JR,Sasitharan T,Marra F

更新日期：2015-08-01 00:00:00

abstract：:This article aims to define a value-based approach to pricing and reimbursement for off-patent originators using a multiple criteria decision analysis (MCDA) approach centered on a systematic analysis of current pricing and reimbursement policies in China. A drug price policy review was combined with a quantitative an...

journal_title：Applied health economics and health policy

authors： Hu S,Zhang Y,He J,Du L,Xu M,Xie C,Peng Y,Wang L

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Generic substitution has been introduced in most countries in order to reduce costs and improve access to drugs. However, regulations and the generic drugs available vary between countries. It is the prescriber or dispenser of the drug who is the final decision maker. Nevertheless, physicians'...

journal_title：Applied health economics and health policy

authors： Toverud EL,Hartmann K,Håkonsen H

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Patients with venous thromboembolism (VTE) commonly have an underlying genetic predisposition. However, genetic tests nowadays in use have very low sensitivity for identifying subjects at risk of VTE. Thrombo inCode(®) is a new genetic tool that has demonstrated very good sensitivity, thanks to very good cov...

journal_title：Applied health economics and health policy

authors： Rubio-Terrés C,Soria JM,Morange PE,Souto JC,Suchon P,Mateo J,Saut N,Rubio-Rodríguez D,Sala J,Gracia A,Pich S,Salas E

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:In Slovenia during the period 2000-2010, the number of years of potential life lost before the age of 70 years per 100,000 population under 70 years of age declined 25 %. OBJECTIVE:The aim of this study was to test the hypothesis that pharmaceutical innovation played a key role in reducing premature mortali...

journal_title：Applied health economics and health policy

authors： Lichtenberg FR

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:There is limited understanding of the health economic implications of cervical screening with human papillomavirus (HPV)-16/18 genotyping. OBJECTIVE:The aim of this study was to evaluate the cost effectiveness of cervical cancer primary screening with a HPV-16/18 genotyping test which simultaneously detects...

journal_title：Applied health economics and health policy

authors： Huh WK,Williams E,Huang J,Bramley T,Poulios N

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Concerns about the long-term sustainability of health care expenditures (HCEs), particularly prescribing expenditures, has become an important policy issue in most developed countries. Previous studies suggest that proximity to death (PTD) has a significant effect on total HCEs, with its exclusion leading to...

journal_title：Applied health economics and health policy

authors： Moore PV,Bennett K,Normand C

更新日期：2014-12-01 00:00:00

abstract：:A routine part of the process for developing National Institute for Health and Care Excellence (NICE) medical technologies guidance is a submission of clinical and economic evidence by the technology manufacturer. The Birmingham and Brunel Consortium External Assessment Centre (EAC; a consortium of the University of B...

journal_title：Applied health economics and health policy

authors： Higgins A,Glover M,Yang Y,Bayliss S,Meads C,Lord J

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:This research seeks to identify the relationship between economic factors related to the ability to receive and pay for health services and adverse cancer outcomes, as well as preventative screening and behavioral factors that influence the risk of cancer. We focus on the Northern High Plains region, where w...

journal_title：Applied health economics and health policy

authors： Belasco EJ,Gong G,Pence B,Wilkes E

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Costs of chronic wound care are significant, but systematic reviews of cost-effectiveness studies regarding guideline-based or strategic interventions are scarce. OBJECTIVES:Our objectives were to assess/compare the cost effectiveness of new interventions/systems designed to improve the prevention/treatment...

journal_title：Applied health economics and health policy

authors： Carter MJ

更新日期：2014-08-01 00:00:00

abstract：:This paper examines the use of propensity score matching in economic analyses of observational data. Several excellent papers have previously reviewed practical aspects of propensity score estimation and other aspects of the propensity score literature. The purpose of this paper is to compare the conceptual foundation...

journal_title：Applied health economics and health policy

authors： Crown WH

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Liposomal amphotericin B (L-AMB) and amphotericin B lipid complex (ABLC) are both indicated for treating invasive fungal infections (IFIs) caused by Aspergillus, Candida and Cryptococcus spp. among patients who are refractory to or intolerant of conventional amphotericin B (CAB). Prior studies have suggested...

journal_title：Applied health economics and health policy

authors： Yang H,Chaudhari P,Zhou ZY,Wu EQ,Patel C,Horn DL

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Cost-effectiveness analyses (CEAs) have been performed for oral non-disease-altering osteoarthritis (OA) treatments for well over a decade. During that period the methods for performing these analyses have evolved as pharmacoeconomic methods have advanced, new treatments have been introduced, and the knowled...

journal_title：Applied health economics and health policy

authors： Wielage RC,Myers JA,Klein RW,Happich M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Treatment with antipsychotic medication is an important element of relapse prevention in the management of schizophrenia, and can reduce inpatient stays. Recently, the long-acting atypical antipsychotic paliperidone long-acting injectable (PLAI), a once-monthly LAI antipsychotic, was approved for treatment o...

journal_title：Applied health economics and health policy

authors： Zeidler J,Mahlich J,Greiner W,Heres S

更新日期：2013-10-01 00:00:00

abstract：:The South Korean Government recently announced a reform in the drug anti-rebate law, with the purpose of eradicating pervasive, unethical, and illegal rebate practices in pharmaceutical marketing. The main objective of this reform is to have the ability to bring criminal charges against doctors and pharmacists for rec...

journal_title：Applied health economics and health policy

authors： Yu SY,Yang BM,Kim JH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The clinical management of intracranial aneurysms is debated in many countries because of the associated disability risk and costs. Therefore, estimating the costs and explaining their variability will provide important information for decision makers. OBJECTIVE:We aimed to evaluate the acute and post-acute...

journal_title：Applied health economics and health policy

authors： Calciolari S,Torbica A,Tarricone R

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Response to growth hormone (GH) therapy may vary between individual patients. Therefore the use of GH in children should be closely monitored to avoid over, under, or ineffective treatment regimens. The treatment response can be evaluated using growth prediction models. In an effort to improve the accuracy o...

journal_title：Applied health economics and health policy

authors： Kaspers S,Ranke MB,Han D,Loftus J,Wollmann H,Lindberg A,Roelants M,Kleintjens J

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:European guidelines advocate the measurement of on-treatment hepatitis C virus (HCV) RNA in order to determine optimal therapy duration (response-guided therapy [RGT]) in patients with rapid virological response (RVR) or delayed virological response (DVR). Treatment response is highly dependent upon the exte...

journal_title：Applied health economics and health policy

authors： McEwan P,Kim R,Yuan Y

更新日期：2013-02-01 00:00:00

abstract：:Economic models are developed to provide decision makers with information related to the real-world effectiveness of therapeutics, screening and diagnostic regimens. Although compliance with these regimens often has a significant impact on real-world clinical outcomes and costs, compliance and persistence have histori...

journal_title：Applied health economics and health policy

authors： Kadambi A,Leipold RJ,Kansal AR,Sorensen S,Getsios D

更新日期：2012-11-01 00:00:00

abstract：:This article deals with the accuracy of statistical records used for political decision making and international comparative analysis. In developing countries, even major macroeconomic indicators can include data inadequacies and methodological differences in data generation between statistical agencies. Existing data...

journal_title：Applied health economics and health policy

authors： Lorenz C

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Canadian patients, healthcare providers and payers share interest in assessing the value of self-monitoring of blood glucose (SMBG) for individuals with type 2 diabetes but not on insulin. Using the UKPDS (UK Prospective Diabetes Study) model, the Canadian Optimal Prescribing and Utilization Service (COMPUS)...

journal_title：Applied health economics and health policy

authors： Tunis SL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a rare but fatal disease. Little is known about the economic burden associated with PAH patients in the US. OBJECTIVES:The objective of this study was to estimate excess direct costs associated with privately insured PAH patients in the US. METHODS:From a privately ...

journal_title：Applied health economics and health policy

authors： Kirson NY,Birnbaum HG,Ivanova JI,Waldman T,Joish V,Williamson T

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:In virologically suppressed patients, switching to darunavir/ritonavir (DRV/r) monotherapy maintains HIV RNA suppression, and could also lower treatment costs. OBJECTIVE:The purpose of this analysis was to calculate the potential cost savings from the use of DRV/r monotherapy in the UK. METHODS:In the MONE...

journal_title：Applied health economics and health policy

authors： Gazzard B,Hill A,Anceau A

更新日期：2011-07-01 00:00:00

abstract：:The debate surrounding whether the findings of efficacy studies are applicable to real-world treatment situations is ongoing. The issue of lack of applicability due to a lack of clinical heterogeneity could be addressed by employing less restrictive inclusion criteria. Given that health economic assessments based on c...

journal_title：Applied health economics and health policy

authors： Richter A,Thieda P,Thaler K,Gartlehner G

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Osteoporosis is recognized as a serious health condition in developed as well as developing countries. There are no accurate estimates of the extent of the burden of osteoporosis in New Zealand. The purpose of this study was to estimate the economic burden of osteoporosis in New Zealand using data from inter...

journal_title：Applied health economics and health policy

authors： Brown P,McNeill R,Leung W,Radwan E,Willingale J

更新日期：2011-03-01 00:00:00

abstract：:In Germany, the Institute for Quality and Efficiency in Health Care (IQWiG) makes recommendations for ceiling prices of drugs based on an evaluation of the relationship between costs and effectiveness. To set ceiling prices, IQWiG uses the following decision rule: the incremental cost-effectiveness ratio (ICER) of a n...

journal_title：Applied health economics and health policy

authors： Gandjour A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:little is known about the economics of acquiring and processing the more than 14 million units of red blood cells used annually in the US. OBJECTIVE:to determine the average price paid by hospitals to suppliers for a unit of red blood cells and to identify cost variations by region and facility type and siz...

journal_title：Applied health economics and health policy

authors： Toner RW,Pizzi L,Leas B,Ballas SK,Quigley A,Goldfarb NI

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Opinions on the use of research abstracts in policy decision making are conflicting. We sought to evaluate the influence of research abstracts in guiding decisions of the Joint Oncology Drug Review of Canada (JODR), which conducts clinical and economic reviews of new cancer treatment drugs for ...

journal_title：Applied health economics and health policy

authors： Weizman AV,Griesman J,Bell CM

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:The management of the large patient population in Italy receiving long-term oral anticoagulation therapy (OAT) poses organizational challenges that are traditionally approached with a centralized procedure, relying on hospital-based clinics and/or GPs. However, the availability of near-patient testing device...

journal_title：Applied health economics and health policy

authors： Pradelli L,Iannazzo S,Zaniolo O,Botrugno P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Antiplatelet therapy plays a central role in the prevention of atherothrombotic events. Both acetylsalicylic acid (aspirin) and clopidogrel have been shown to reduce the risk of recurrent cardiovascular events in various subgroups of patients with vascular disease. OBJECTIVE:To estimate the cost effectivene...

journal_title：Applied health economics and health policy

authors： Logman JF,Heeg BM,Herlitz J,van Hout BA

更新日期：2010-01-01 00:00:00

abstract：:The rapid rise in pharmaceutical costs in France has been driven by new technologies and the growing prevalence of chronic diseases as well as considerable prescribing freedom and choice of physician among patients. This has led to the introduction of a number of reforms and initiatives in an attempt to moderate expen...

journal_title：Applied health economics and health policy

authors： Sermet C,Andrieu V,Godman B,Van Ganse E,Haycox A,Reynier JP

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Price, income and health status are likely to affect the demand for healthcare in developing countries, and their quantitative effects are unclear in the literature. Some studies report that prices are not important determinants, while others conclude that prices are important determinants of the demand for ...

journal_title：Applied health economics and health policy

authors： Sarma S

更新日期：2009-01-01 00:00:00

abstract：:The mandatory nature of recommendations made by the National Institute for Health and Clinical Excellence (NICE) in the UK has highlighted inherent difficulties in the process of disinvestment in existing technologies to fund NICE-approved technologies. A lack of evidence on candidate technologies means that the proce...

journal_title：Applied health economics and health policy

authors： Karnon J,Carlton J,Czoski-Murray C,Smith K

更新日期：2009-01-01 00:00:00

abstract：:The biotech industry now accounts for a substantial and growing proportion of total R&D spending on new medicines. However, compared with the pharmaceutical industry, the biotech industry is financially fragile. This article illustrates the financial fragility of the biotech and pharmaceutical industries in the US and...

journal_title：Applied health economics and health policy

authors： Golec J,Vernon JA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is the second most common cancer in Taiwan. For males in Taiwan, it is the most dangerous cancer, with both the highest incidence and mortality rate. OBJECTIVE:To determine cancer-related medical care costs for long-term survivors of HCC. METHODS:The estimation of the lifetim...

journal_title：Applied health economics and health policy

authors： Lang HC,Wu JC,Yen SH,Lan CF,Wu SL

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:It is estimated that annually 300 000 cases of rotavirus-induced gastroenteritis (RVGE) occur in children aged up to 5 years in France. A two-dose vaccine against rotavirus infection (RIX4414; Rotarix, GlaxoSmithKline), has been shown to be highly effective against severe RVGE. OBJECTIVE:This study evaluate...

journal_title：Applied health economics and health policy

authors： Standaert B,Parez N,Tehard B,Colin X,Detournay B

更新日期：2008-01-01 00:00:00

abstract：:The aim of the review is to establish whether, on the basis of previous published evidence, current accepted guidance for health economic evaluation needs to be adapted to evaluate healthcare based on use of genetic information. Online literature search strategies were designed (using PubMed and the NHS Economic Evalu...

journal_title：Applied health economics and health policy

authors： Jarrett J,Mugford M

更新日期：2006-01-01 00:00:00